NRF2 Antikörper (AA 356-589)
Kurzübersicht für NRF2 Antikörper (AA 356-589) (ABIN1724931)
Target
Alle NRF2 (NFE2L2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 356-589
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Verwendungszweck
- NFE2L2 Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human NFE2L2 (AA: 356-589) expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
- ELISA: 1/10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "NFE2L2 pathway polymorphisms and lung function decline in chronic obstructive pulmonary disease." in: Physiological genomics, Vol. 44, Issue 15, pp. 754-63, (2012) (PubMed).
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- NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
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Andere Bezeichnung
- NFE2L2
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Hintergrund
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This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters, many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene.
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Molekulargewicht
- 67.8 kDa
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UniProt
- Q16236
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Pathways
- ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling
Target
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