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AXL Antikörper (pTyr698, pTyr702, pTyr703)

AXL Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN756037
  • Target Alle AXL Antikörper anzeigen
    AXL (AXL Receptor tyrosine Kinase (AXL))
    Bindungsspezifität
    • 18
    • 18
    • 18
    • 15
    • 11
    • 9
    • 8
    • 8
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr698, pTyr702, pTyr703
    Reaktivität
    • 128
    • 66
    • 54
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 115
    • 19
    • 3
    • 1
    Kaninchen
    Klonalität
    • 116
    • 22
    Polyklonal
    Konjugat
    • 56
    • 10
    • 8
    • 8
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser AXL Antikörper ist unkonjugiert
    Applikation
    • 101
    • 57
    • 30
    • 25
    • 25
    • 17
    • 12
    • 9
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Dog,Cow,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human AXL around the phosphorylation site of Tyr698+Tyr702+Tyr703
    Isotyp
    IgG
    Top Product
    Discover our top product AXL Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    AXL (AXL Receptor tyrosine Kinase (AXL))
    Andere Bezeichnung
    AXL+ (AXL Produkte)
    Hintergrund

    Synonyms: Adhesion related kinase, AI323647, Ark, Axl, AXL oncogene, AXL receptor tyrosine kinase, AXL transforming gene, AXL transforming sequence/gene, EC 2.7.10.1, JTK11, Oncogene AXL, Tyro7, Tyrosine protein kinase receptor UFO, Tyrosine-protein kinase receptor UFO, UFO, UFO_HUMAN.

    Background: The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, the Axl protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors such as vitamin K dependent protein growth arrest specific gene 6. It is involved in the stimulation of cell proliferation. This receptor can also mediate cell aggregation by homophilic binding. Axl is a chronic myelogenous leukemia associated oncogene and also associated with colon cancer and melanoma.The Axl gene is evolutionarily conserved between vertebrate species. This gene has two different alternatively spliced transcript variants (AXL1 and AXL2).

    Gen-ID
    558
    Pathways
    RTK Signalweg, Cellular Response to Molecule of Bacterial Origin
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