AXL Antikörper (AXL Receptor tyrosine Kinase)

Details for Product anti-AXL Antibody No. ABIN968974, Anbieter: Anmelden zum Anzeigen
Antigen
  • JTK11
  • UFO
  • AI323647
  • Ark
  • Tyro7
  • Ufo
  • AXL receptor tyrosine kinase
  • Axl receptor tyrosine kinase
  • AXL
  • Axl
Reaktivität
Human
273
116
76
5
2
2
1
1
1
1
Wirt
Maus
188
96
32
2
1
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser AXL Antikörper ist unkonjugiert
14
12
12
11
9
9
8
8
8
8
8
8
6
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
Applikation
Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
197
124
106
71
30
26
17
10
8
5
5
3
3
2
2
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen Purified recombinant extracellular fragment of human AXL fused with hIgGFc tag expressed in HEK293 cell line.
Klon 7-00E-10
Isotyp IgG1
Reinigung Ascites
Plasmids, Primers & others Plasmide, Primers & weitere AXL products on genomics-online (e.g. as negative or positive controls)
Antigen AXL Receptor tyrosine Kinase (AXL)
Andere Bezeichnung AXL (AXL Antibody Abstract)
Hintergrund AXL: AXL receptor tyrosine kinase, also known as UFO, JTK11. Entrez Protein NP_001690. It is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.
Molekulargewicht 97.4 kDa
Gen-ID 558
HGNC 558
Pathways RTK Signalweg, Cellular Response to Molecule of Bacterial Origin
Applikations-hinweise ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C,-20 °C
Informationen zur Lagerung 4°C, -20°C for long term storage
Bilder des Herstellers
Immunocytochemistry (ICC) image for anti-AXL Receptor tyrosine Kinase (AXL) antibody (ABIN968974) Figure 1: Confocal immunofluorescence analysis of methanol-fixed HEK293 cells trasfec...
Western Blotting (WB) image for anti-AXL Receptor tyrosine Kinase (AXL) antibody (ABIN968974) Figure 2: Western blot analysis using AXL mouse mAb against extracellular domain of h...
Produkt verwendet in: Vajkoczy, Knyazev, Kunkel, Capelle, Behrndt, von Tengg-Kobligk, Kiessling, Eichelsbacher, Essig, Read, Erber, Ullrich: "Dominant-negative inhibition of the Axl receptor tyrosine kinase suppresses brain tumor cell growth and invasion and prolongs survival." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 15, pp. 5799-804, 2006 (PubMed).

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