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AXL Antikörper (C-Term)

KO Validated AXL Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2855015
  • Target Alle AXL Antikörper anzeigen
    AXL (AXL Receptor tyrosine Kinase (AXL))
    Bindungsspezifität
    • 20
    • 20
    • 20
    • 16
    • 15
    • 11
    • 11
    • 9
    • 8
    • 8
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 136
    • 62
    • 55
    • 6
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    Human
    Wirt
    • 123
    • 19
    • 3
    • 1
    Kaninchen
    Klonalität
    • 123
    • 23
    Polyklonal
    Konjugat
    • 59
    • 12
    • 11
    • 10
    • 8
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser AXL Antikörper ist unkonjugiert
    Applikation
    • 117
    • 70
    • 38
    • 26
    • 26
    • 21
    • 14
    • 9
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human
    Produktmerkmale
    Rabbit Polyclonal antibody to AXL (AXL receptor tyrosine kinase)
    AXL antibody [C2C3], C-term
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Güteklasse
    KO Validated
    Immunogen
    Recombinant protein encompassing a sequence within the C-terminus region of human AXL. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product AXL Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: H1299 , AXL transfected 293T , HeLa

    Validation: KO/KD, Overexpression

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.34 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    AXL (AXL Receptor tyrosine Kinase (AXL))
    Andere Bezeichnung
    AXL receptor tyrosine kinase (AXL Produkte)
    Synonyme
    JTK11 antikoerper, UFO antikoerper, AI323647 antikoerper, Ark antikoerper, Tyro7 antikoerper, Ufo antikoerper, AXL receptor tyrosine kinase antikoerper, Axl receptor tyrosine kinase antikoerper, AXL antikoerper, Axl antikoerper
    Hintergrund
    The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.

    Cellular Localization: Membrane, Single-pass type I membrane protein
    Molekulargewicht
    98 kDa
    Gen-ID
    558
    UniProt
    P30530
    Pathways
    RTK Signalweg, Cellular Response to Molecule of Bacterial Origin
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