PDK2 Antikörper (AA 315-407)
Kurzübersicht für PDK2 Antikörper (AA 315-407) (ABIN751783)
Target
Alle PDK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 315-407
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Kreuzreaktivität
- Human, Ratte
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Homologie
- Mouse,Dog,Cow,Pig,Horse,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human PDK2
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Isotyp
- IgG
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Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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- PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))
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Andere Bezeichnung
- PDK2
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Hintergrund
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Synonyms: PDHK2, Pyruvate dehydrogenase kinase isoform 2, pyruvate dehydrogenase kinase, isozyme 2, Pyruvate dehydrogenase lipoamide kinase isozyme 2, mitochondrial, PDK2_HUMAN.
Background: This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010].
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Gen-ID
- 5164
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Pathways
- PI3K-Akt Signalweg, RTK Signalweg, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effekt
Target
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