IFI16 Antikörper (AA 183-743) (Cy3)

Produktnummer ABIN8001420

Der Kaninchen Polyklonal anti-IFI16 Antikörper wird verwendet zum Nachweis von IFI16 in Proben von Human, Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für IFI16 Antikörper (AA 183-743) (Cy3) (ABIN8001420)

Target: IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFI16 Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-IFI16 Antikörper (Cy3)

Bindungsspezifität: AA 183-743

Verwendungszweck: Anti-IFI16 Antibody Cy3 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human IFI16 recombinant protein (Position: E183-K743).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu IFI16

Target: IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))

Andere Bezeichnung: IFI16

Hintergrund:

Background: Gamma-interferon-inducible protein Ifi-16 (Ifi-16) also known as interferon-inducible myeloid differentiation transcriptional activator is a protein that in humans is encoded by the IFI16 gene. This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: interferon gamma inducible protein 16

Gen-ID: 3428

UniProt: Q16666

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Autophagie, Inflammasome