Rekombinanter IFI16 Antikörper (AA 350-400)
Kurzübersicht für Rekombinanter IFI16 Antikörper (AA 350-400) (ABIN7795821)
Target
Alle IFI16 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 350-400
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Verwendungszweck
- Rabbit anti-IFI16 Recombinant Monoclonal Antibody [BLR375N]
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Aufreinigung
- Purified
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Immunogen
- between 350 and 400
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Isotyp
- IgG
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Applikationshinweise
- WB,11000,IP,20 μL/mg lysate,IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 250 μg/mL
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Buffer
- Phosphate Buffered Saline (PBS) with 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- 2 - 8 °C
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Haltbarkeit
- 12 months
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- IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))
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Andere Bezeichnung
- IFI16
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Hintergrund
- Gamma-interferon-inducible protein 16 (aka IFI16) is a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. IFI16 contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions and localizes to the nucleoplasm and nucleoli. IFI16 interacts with p53 and retinoblastoma-1, modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. [taken from NCBI Entrez Gene (Gene ID: 3428)].
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Gen-ID
- 3428
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UniProt
- Q16666
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Pathways
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Autophagie, Inflammasome
Target
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