Growth Hormone Receptor Antikörper (AA 19-638) (Cy3)

Produktnummer ABIN7995494

Der Cy3-konjugierte Kaninchen Polyklonal anti-Growth Hormone Receptor Antikörper (ABIN7995494) detektiert spezifisch Growth Hormone Receptor in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Growth Hormone Receptor Antikörper (AA 19-638) (Cy3) (ABIN7995494)

Target: Growth Hormone Receptor (GHR)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Growth Hormone Receptor Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Growth Hormone Receptor Antikörper (Cy3)

Bindungsspezifität: AA 19-638

Verwendungszweck: Anti-Growth hormone receptor/GHR Antibody Cy3 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Growth hormone receptor/GHR recombinant protein (Position: F19-P638).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Growth Hormone Receptor

Target: Growth Hormone Receptor (GHR)

Andere Bezeichnung: GHR

Hintergrund:

Background: Growth hormone receptor is a protein that in humans is encoded by the GHR gene. It is mapped to 5p13.1-p12. This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.

Gene Full Name: growth hormone receptor

Gen-ID: 2690

UniProt: P10912

Pathways: NF-kappaB Signalweg, JAK-STAT Signalweg, Response to Growth Hormone Stimulus