Cullin 2 Antikörper (AA 389-745) (Fluoro550)

Produktnummer ABIN7982002

Der Kaninchen Polyklonal anti-Cullin 2 Antikörper wird verwendet zum Nachweis von Cullin 2 in Proben von Human, Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für Cullin 2 Antikörper (AA 389-745) (Fluoro550) (ABIN7982002)

Target: Cullin 2 (CUL2)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cullin 2 Antikörper ist konjugiert mit Fluoro550

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Cullin 2 Antikörper (Fluoro550)

Bindungsspezifität: AA 389-745

Verwendungszweck: Anti-CUL2 Antibody Fluoro550 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human CUL2 recombinant protein (Position: E389-A745).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Cullin 2

Target: Cullin 2 (CUL2)

Andere Bezeichnung: CUL2

Hintergrund:

Background: Cullin 2 (CUL2) is a protein that in humans is encoded by the CUL2 gene. Using immunofluorescence, it is showed that CUL2 is a cytosolic protein that can be translocated to the nucleus by VHL. By fluorescence in situ hybridization, this gene is mapped to 10p11.2-p11.1, a region reported to show loss of heterozygosity (LOH) in several forms of human cancer, including non-clear cell renal cell carcinoma. CUL2 may serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.

Gene Full Name: cullin 2

Gen-ID: 8453

UniProt: Q13617

Pathways: M Phase, Asymmetric Protein Localization, SARS-CoV-2 Protein Interaktom