Rekombinanter NRF2 Antikörper

Produktnummer ABIN7938378

Der Kaninchen Monoklonal anti-NRF2 Antikörper (Klon 1I21) (ABIN7938378) detektiert spezifisch NRF2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Rekombinanter NRF2 Antikörper (ABIN7938378)

Target: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser NRF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 1I21

Produktdetails anti-NRF2 Antikörper

Verwendungszweck: NRF2 antibody (rAb), 100 μl (Clone 1I21)

Aufreinigung: Protein A Chromatography

Immunogen: This antibody was raised against the NRF2 fusion protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000-1:5000 dilution

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Details zu NRF2

Target: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Andere Bezeichnung: NRF2

Hintergrund:

Background_Plain: NRF2 (NF-E2-Related Factor 2) is a transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.

Aliases: NFE2L2

Molekulargewicht: 68 kDa

Pathways: ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling