PKM2 Antikörper
Kurzübersicht für PKM2 Antikörper (ABIN7882118)
Target
Alle PKM2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Verwendungszweck
- PKM2 Antibody / Pyruvate Kinase
-
Aufreinigung
- Affinity purified
-
Immunogen
- A synthetic peptide specific to human PKM2 was used as the immunogen for the PKM2 antibody.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- Optimal dilution of the PKM2 antibody should be determined by the researcher.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store the PKM2 antibody at -20oC.
-
-
- PKM2 (Pyruvate Kinase M2 (PKM2))
-
Andere Bezeichnung
- PKM2
-
Hintergrund
- The PKM gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [RefSeq]
-
UniProt
- P14618
-
Pathways
- Warburg Effekt
Target
-