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PKM2 Antikörper (N-Term)

Name: PKM2 Antikörper (N-Term)
SKU: ABIN391052
Price: 445.5 EUR
Availability: InStock

PKM2 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB5870 unconjugated

All lanes : Anti-PKM2 antibody at 1:2000 dilution Lane 1: MCF-7 whole cell lysates Lane 2: Hela whole cell lysates Lane 3: NIH/3T3 whole cell lysates Lane 4: PC-12 whole cell lysates Lysates/proteins at 20 μg per lane. (PKM2 Antikörper (N-Term))

All lanes : Anti-PKM2 antibody at 1:2000 dilution Lane 1: MCF-7 whole cell lysates Lane 2: Hela whole cell lysates Lane 3: THP-1 whole cell lysates Lane 4: NIH/3T3 whole cell lysates Lane 5: PC-12 whole cell lysates Lysates/proteins at 20 μg per lane. (PKM2 Antikörper (N-Term))

2 Abbildungen

(1 reference)

Produktnummer ABIN391052

Datenblatt (PDF)

Target Alle PKM2 Antikörper anzeigen

PKM2 (Pyruvate Kinase M2 (PKM2))
Bindungsspezifität
16

16

15

12

7

7

7

7

7

6

6

5

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 121-151, N-Term
Reaktivität
147

100

88

5

4

3

2

2

2

2

1

1

1
Human, Maus
Wirt
124

22

5

1
Kaninchen
Passende Sekundärantikörper
Klonalität
130

22
Polyklonal
Konjugat
60

13

10

10

10

10

10

10

3

3

2

2

2

2

2

2

1
Dieser PKM2 Antikörper ist unkonjugiert
Applikation
88

36

27

27

24

20

17

15

10

7

7

5

2

2

2

1

1

1
Western Blotting (WB)

Homologie

Rb, Rat

Aufreinigung

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen

This Pyruvate Kinase (PKM2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-151 amino acids from the N-terminal region of human Pyruvate Kinase (PKM2).

Klon

RB5870

Isotyp

Ig Fraction

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PKM2 Reaktivität: Human, Maus, Ratte, Affe WB, IHC (p), IF Wirt: Kaninchen Polyclonal RB3697 unconjugated

anti-Pyruvate Kinase M2 (PKM2) (pTyr105) antibody
PKM2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 383-417), (C-Term) antibody
PKM2 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB18405 unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 476-505) antibody
PKM2 Reaktivität: Human, Maus, Ratte, Primate WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 116-145) antibody
PKM2 Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Kaninchen Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 255-350) antibody
PKM2 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IHC (p), IF (cc), IF (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 116-145), (N-Term) antibody
PKM2 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB15338 unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 1-531) antibody
PKM2 Reaktivität: Human WB, PLA Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB: 1:2000. WB: 1:2000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Shin, Yoo, Hong, Chang, Jung, Jeong, Park: "Upregulation of glycolytic enzymes in proteins secreted from human colon cancer cells with 5-fluorouracil resistance." in: Electrophoresis, Vol. 30, Issue 12, pp. 2182-92, (2009) (PubMed).
Target

PKM2 (Pyruvate Kinase M2 (PKM2))

Andere Bezeichnung

Pyruvate Kinase (PKM2) (PKM2 Produkte)

Synonyme

CTHBP antikoerper, OIP3 antikoerper, PK3 antikoerper, PKM2 antikoerper, TCB antikoerper, THBP1 antikoerper, AA414905 antikoerper, AL024370 antikoerper, AL024424 antikoerper, Pk-2 antikoerper, Pk-3 antikoerper, Pk3 antikoerper, Pkm2 antikoerper, PKM12 antikoerper, PKM antikoerper, pyruvate kinase M1/2 antikoerper, pyruvate kinase, muscle antikoerper, PKM antikoerper, Pkm antikoerper

Hintergrund

PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.

Molekulargewicht

57937

Gen-ID

5315

NCBI Accession

NP_001193725, NP_001193726, NP_001193727, NP_001193728, NP_002645, NP_872270, NP_872271

UniProt

P14618

Pathways

Warburg Effekt