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PKM2 Antikörper (C-Term)

PKM2 Reaktivität: Human, Maus, Ratte, Affe WB, IHC (p), IF Wirt: Kaninchen Polyclonal RB3697 unconjugated
Produktnummer ABIN391053
  • Target Alle PKM2 Antikörper anzeigen
    PKM2 (Pyruvate Kinase M2 (PKM2))
    Bindungsspezifität
    • 16
    • 16
    • 16
    • 15
    • 12
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 476-505, C-Term
    Reaktivität
    • 157
    • 100
    • 87
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Affe
    Wirt
    • 134
    • 22
    • 5
    • 1
    Kaninchen
    Klonalität
    • 140
    • 22
    Polyklonal
    Konjugat
    • 60
    • 15
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PKM2 Antikörper ist unkonjugiert
    Applikation
    • 98
    • 46
    • 27
    • 27
    • 25
    • 24
    • 18
    • 16
    • 10
    • 7
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This Pyruvate Kinase (PKM2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-505 amino acids from the C-terminal region of human Pyruvate Kinase (PKM2).
    Klon
    RB3697
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product PKM2 Primärantikörper
  • Applikationshinweise
    IF: 1:200. WB: 1:1000. WB: 1:1000. WB: 1:2000. IHC-P: 1:50~1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid freeze-thaw cycles.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
    Haltbarkeit
    6 months
  • Kienzl, Sarg, Golderer, Obrist, Werner, Werner-Felmayer, Lindner, Maglione, Schneeberger, Margreiter, Brandacher: "Proteomic profiling of acute cardiac allograft rejection." in: Transplantation, Vol. 88, Issue 4, pp. 553-60, (2009) (PubMed).

  • Target
    PKM2 (Pyruvate Kinase M2 (PKM2))
    Andere Bezeichnung
    PKM2 (PKM2 Produkte)
    Synonyme
    CTHBP antikoerper, OIP3 antikoerper, PK3 antikoerper, PKM2 antikoerper, TCB antikoerper, THBP1 antikoerper, AA414905 antikoerper, AL024370 antikoerper, AL024424 antikoerper, Pk-2 antikoerper, Pk-3 antikoerper, Pk3 antikoerper, Pkm2 antikoerper, PKM12 antikoerper, PKM antikoerper, pyruvate kinase M1/2 antikoerper, pyruvate kinase, muscle antikoerper, PKM antikoerper, Pkm antikoerper
    Hintergrund
    There are 4 isozymes of pyruvate kinase in mammals: L, R, M1 and M2. PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.
    Molekulargewicht
    57937
    Gen-ID
    5315
    NCBI Accession
    NP_001193725, NP_001193726, NP_001193727, NP_001193728, NP_002645, NP_872270, NP_872271
    UniProt
    P14618
    Pathways
    Warburg Effekt
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