NPM1 Antikörper (pThr95) (Biotin)

Produktnummer ABIN744400

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NPM1 in ELISA, IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für NPM1 Antikörper (pThr95) (Biotin) (ABIN744400)

Target: NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NPM1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-NPM1 Antikörper (Biotin)

Bindungsspezifität: pThr95

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human NPM around the phosphorylation site of Thr95

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu NPM1

Target: NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))

Andere Bezeichnung: NPM

Hintergrund:

Synonyms: Nucleophosmin phospho T95, Nucleophosmin phospho Thr95, p-Nucleophosmin Thr95, B23, B23, MGC104254, NMP1, NMP1, NO38, NPM 1, NPM, NPM_HUMAN, NPM1, Nucleolar Phosphoprotein B23, Nucleolar Phosphoprotein B23, Nucleolar protein NO38, Nucleophosmin nucleolar phosphoprotein B23 numatrin, Nucleophosmin, Nucleophosmin/B23.2, Nucleophosmin/nucleoplasmin family member 1, Nucleoplasmin Family Member 1, Nucleoplasmin Family Member 1, Numatrin, Numatrin, OTTHUMP00000161024, OTTHUMP00000161025, OTTHUMP00000223397, OTTHUMP00000223398, TRK fused gene.

Background: This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009].

Gen-ID: 4869

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly