MAP2K7 Antikörper (pSer271, pThr275) (Biotin)

Produktnummer ABIN743920

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MAP2K7 in WB, ELISA, IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für MAP2K7 Antikörper (pSer271, pThr275) (Biotin) (ABIN743920)

Target: MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP2K7 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-MAP2K7 Antikörper (Biotin)

Bindungsspezifität: pSer271, pThr275

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human MKK7 around the phosphorylation site of Ser271/Thr275

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu MAP2K7

Target: MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

Andere Bezeichnung: MKK7 +

Hintergrund:

Synonyms: MEK7 phospho S277 + T275, MEK7 phospho Ser277 + Thr275, p-MEK7 S277 + T275, p-MEK7 Ser277 + Thr275, c-Jun N-terminal kinase kinase 2, Dual specicity mitogen activated protein kinase kinase 7, Dual specicity mitogen-activated protein kinase kinase 7, JNK activating kinase 2, JNK kinase 2, JNK-activating kinase 2, Jnkk 2, Jnkk-2, Jnkk2, MAP kinase kinase 7, MAP2K7, MAPK/ERK kinase 7, MAPKK 7, MAPKK-7, MAPKK7, MEK 7, Mitogen Activated Protein Kinase kinase 7, MKK 7, MKK-7, MKK7, MP2K7_HUMAN, PRKMK 7, PRKMK-7, PRKMK7, Sek 2, Sek-2, Sek2.

Background: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined. [provided by RefSeq, Jul 2008].

Gen-ID: 5609

Pathways: MAPK Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling