IFI16 Antikörper (AA 183-743)

Produktnummer ABIN7871472

Der Maus Monoklonal anti-IFI16 Antikörper wird verwendet zum Nachweis von IFI16 in Proben von Human. Er wurde validiert für WB, IF und FACS.

Kurzübersicht für IFI16 Antikörper (AA 183-743) (ABIN7871472)

Target: IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IFI16 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: 2I3D7

Produktdetails anti-IFI16 Antikörper

Bindungsspezifität: AA 183-743

Verwendungszweck: IFI16 Antibody / Gamma-interferon-inducible protein 16

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids E183-K743) was used as the immunogen for the IFI16 antibody.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the IFI16 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the IFI16 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu IFI16

Target: IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))

Andere Bezeichnung: IFI16

Hintergrund: Gamma-interferon-inducible protein Ifi-16 (Ifi-16) also known as interferon-inducible myeloid differentiation transcriptional activator is a protein that in humans is encoded by the IFI16 gene. This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniProt: Q16666

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Autophagie, Inflammasome