XPC Antikörper (AA 146-838)

Produktnummer ABIN7870736

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch XPC in WB, ELISA, FACS und IF. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus und Affe.

Kurzübersicht für XPC Antikörper (AA 146-838) (ABIN7870736)

Target: XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))

Reaktivität: Human, Ratte, Maus, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XPC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Produktdetails anti-XPC Antikörper

Bindungsspezifität: AA 146-838

Verwendungszweck: XPC Antibody

Aufreinigung: Affinity purified

Immunogen: Recombinant human protein (amino acids D146-E838) was used as the immunogen for the XPC antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the XPC antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the XPC antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu XPC

Target: XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))

Andere Bezeichnung: XPC

Hintergrund: Xeroderma pigmentosum, complementation group C, also known as XPC, is a protein which in humans is encoded by the XPC gene. The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.

UniProt: Q01831

Pathways: p53 Signalweg, DNA Reparatur