TRADD Antikörper (AA 126-151)

Produktnummer ABIN7870387

Der Kaninchen Polyklonal anti-TRADD Antikörper (ABIN7870387) detektiert spezifisch TRADD in WB, IF, IHC (p) und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für TRADD Antikörper (AA 126-151) (ABIN7870387)

Target: TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRADD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-TRADD Antikörper

Bindungsspezifität: AA 126-151

Verwendungszweck: TNFR1-associated DEATH domain protein Antibody / TRADD

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 126-151 from the human protein was used as the immunogen for the TRADD antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the TRADD antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the TRADD antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu TRADD

Target: TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

Andere Bezeichnung: TNFR1-associated DEATH domain protein

Hintergrund: The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq].

UniProt: Q15628

Pathways: NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Hepatitis C