GATA4 Antikörper (AA 1-332)

Produktnummer ABIN7869201

Der Kaninchen Polyklonal anti-GATA4 Antikörper wird verwendet zum Nachweis von GATA4 in Proben von Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für GATA4 Antikörper (AA 1-332) (ABIN7869201)

Target: GATA4 (GATA Binding Protein 4 (GATA4))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GATA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GATA4 Antikörper

Bindungsspezifität: AA 1-332

Verwendungszweck: Zebrafish Gata4 Antibody / GATA-binding factor 4

Aufreinigung: Antigen affinity chromatography

Immunogen: E. coli-derived zebrafish Gata4 recombinant protein (amino acids M1-M332) was used as the immunogen for the Zebrafish Gata4 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Zebrafish Gata4 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Zebrafish Gata4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu GATA4

Target: GATA4 (GATA Binding Protein 4 (GATA4))

Andere Bezeichnung: Gata4

Hintergrund: GATA-binding factor 4 (Gata4) is a zinc finger transcription factor belonging to the GATA family, which regulates gene expression during embryonic development and cell differentiation. In zebrafish (Danio rerio), Gata4 plays a critical role in the development of the heart, endoderm, and gastrointestinal tract, mirroring its conserved function in vertebrate organogenesis.

Gata4 is expressed early during zebrafish embryogenesis, particularly in the cardiac mesoderm and endodermal precursors. It functions as a key regulator of cardiomyocyte differentiation, heart tube formation, and gut development. Gata4 also interacts with other transcription factors such as Nkx2.5 and Tbx5 to coordinate cardiac gene expression programs.

Due to its essential role in heart development and its evolutionary conservation, zebrafish Gata4 is widely studied in models of congenital heart disease, organ specification, and regenerative biology. It serves as a valuable molecular marker and research target for developmental biology, gene regulation, and disease modeling.

UniProt: Q09JY7

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis