IL-6 Antikörper (AA 1-200)

Produktnummer ABIN7858570

Der Maus Monoklonal anti-IL-6 Antikörper (Klon IL6-4642) (ABIN7858570) detektiert spezifisch IL-6 in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für IL-6 Antikörper (AA 1-200) (ABIN7858570)

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL-6 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: IL6-4642

Produktdetails anti-IL-6 Antikörper

Bindungsspezifität: AA 1-200

Verwendungszweck: IL-6 (Interleukin-6) / Interferon beta-2 (Hybridoma Growth Factor) Antibody

Spezifität: IL-6 is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B-cells and T-cells. It plays a critical role in B-cell differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma. IL-6 is produced by a variety of cell types, including monocytes, fibroblasts and endothelial cells. Upon stimulation, macrophages, T, B, mast, and glial cells, eosinophils, keratinocytes and granulocytes also secrete IL-6.It is involved in host defense, acute phase reactions, immune responses, and hematopoiesis.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-200) of human IL-6 protein (exact sequence is proprietary)

Isotyp: IgG2, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu IL-6

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Andere Bezeichnung: IL-6

Hintergrund:

B-cell stimulatory factor 2 (BSF-2), CTL differentiation factor (CDF), Cytotoxic T cell differentiation factor, Hepatocyte stimulating factor (HSF), HPGF, Hybridoma growth factor Interferon beta-2, Hybridoma plasmacytoma growth factor, IFN-beta-2 (IFNB2)

Human heart or adrenal gland. Stimulated peritoneal macrophages.

Molekulargewicht: 21kDa

Gen-ID: 3569, 654458

UniProt: P05231

Pathways: TLR Signalweg, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagie, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome