Rekombinanter CD40 Antikörper

Produktnummer ABIN7865479

Dieser Maus Monoklonal Antikörper detektiert spezifisch CD40 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter CD40 Antikörper (ABIN7865479)

Target: CD40

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD40 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: R11E9

Produktdetails anti-CD40 Antikörper

Expressionssystem: CHO Cells

Verwendungszweck: Recombinant CD40 / TNFRSF5 Antibody

Spezifität: The CD40 antigen is a single chain glycoprotein with a calculated molecular weight of 27 kD. It is known to be a member of the tumor necrosis factor/nerve growth factor superfamily and shows a significant homology to the Hodgkin,Ä111s disease-associated antigen, CD30. The precise function of the CD40 antigen is unknown, but it appears to be involved in the transduction of regulatory signals for cellular functions such as B cell proliferation and differentiation. It is also important in the prevention of apoptosis of germinal centre B cells. The CD40 antigen is found on mature B cells (except plasma cells), interdigitating reticulum cells and follicular dendritic cells.

Aufreinigung: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogen: Prokaryotic recombinant fusion protein corresponding to the entire external domain of the CD40 molecule

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu CD40

Target: CD40

Andere Bezeichnung: CD40

Hintergrund:

TNFRSF5

Human spleen, lymph node or tonsil.

Molekulargewicht: 43kDa

Gen-ID: 958, 472860

UniProt: P25942

Pathways: NF-kappaB Signalweg, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints