TNF alpha Antikörper

Produktnummer ABIN8063041

Dieser Maus Monoklonal Antikörper detektiert spezifisch TNF alpha in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für TNF alpha Antikörper (ABIN8063041)

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TNF alpha Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: MAb11

Produktdetails anti-TNF alpha Antikörper

Verwendungszweck: Purified Anti-Human TNF-α Antibody[MAb11]

Aufreinigung: >98%, Protein A/G purified

Reinheit: >98 %

Immunogen: Recombinant Human TNF-alpha protein

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: FCM 2 μg/mL(0.5x106-1x106 cells)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: ≥ 1 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.05 % non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu TNF alpha

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Andere Bezeichnung: TNF-alpha

Hintergrund: Tumor Necrosis Factor Ligand Superfamily Member,TNFSF,TNF,DIF,TNF-alpha,TNFA,TNFSF2,TNLG1F,TNF alpha,Cachectin,Tumor Necrosis Factor,Tumor Necrosis Factor Ligand Superfamily Member 2,TNF-a,APC1,APC1 protein,DIF,TNF-alpha,TNFA,TNFSF2,Differentiation inducing factor,Macrophage cytotoxic factor,macrophage derived,member 2,Membrane Form,monocyte derived,soluble form,sTNFA,TNF superfamily,Tumor necrosis factor alpha,This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: P01375

Pathways: NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome