TNF alpha Antikörper
Kurzübersicht für TNF alpha Antikörper (ABIN8062987)
Target
Alle TNF alpha Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Purified Anti-Mouse TNF-α Antibody[TN3-19.12]
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Aufreinigung
- >98%, Protein A/G purified
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Reinheit
- >98 %
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Immunogen
- Recombinant Mouse TNF-alpha protein
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Isotyp
- IgG2, kappa
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Applikationshinweise
- FCM 2 μg/mL(0.5x106-1x106 cells)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- ≥ 1 mg/mL
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Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.05 % non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
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Haltbarkeit
- 12 months
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- TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
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Andere Bezeichnung
- TNF-alpha
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Hintergrund
- Tumor necrosis factor ligand superfamily member,TNFSF,DIF,Tnfa,TNF-a,TNFSF2,Tnlg1f,Tnfsf1a,TNFalpha,TNF-alpha,ICD1,ICD2,Membrane Form,N-terminal fragment,NTF,Tnf,Cachectin,Tumor necrosis factor,Tumor necrosis factor ligand superfamily member 2,Tnfa,TNF-a,TNFalpha,TNF-alpha,Tnfsf1a,TNFSF2,Tnlg1f,TNFSF2,TNF,TNFa,Tumor necrosis factor alpha (TNF-alpha, TNF- alpha, TNFA ), also known as Cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, immune system development, apoptosis, and lipid metabolism. TNF-alpha is produced by several lymphoid cells as well as by astrocytes, endothelial cells, and smooth muscle cells. Mouse TNF-alpha consists of a 35 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 179 aa extracellular domain (ECD). Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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UniProt
- P06804
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Pathways
- NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
Target
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