Rekombinanter PPP1CB Antikörper

Produktnummer ABIN7828499

Der Kaninchen Monoklonal anti-PPP1CB Antikörper wird verwendet zum Nachweis von PPP1CB in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC, IF, IP und FACS.

Kurzübersicht für Rekombinanter PPP1CB Antikörper (ABIN7828499)

Target: PPP1CB (Protein Phosphatase 1, Catalytic Subunit, beta Isoform (PPP1CB))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PPP1CB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)

Klon: A337

Produktdetails anti-PPP1CB Antikörper

Verwendungszweck: Recombinant PPP1CB Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human PPP1CB fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000,IHC 1:50-1:100,IF 1:200-1:500,FCM 1:50-1:100,IP 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu PPP1CB

Target: PPP1CB (Protein Phosphatase 1, Catalytic Subunit, beta Isoform (PPP1CB))

Andere Bezeichnung: PPP1CB

Hintergrund: NSLH,PPP1CB,HEL-S-80p,PP-1B,PP1B,PP1beta,PPP1CD,NSLH2,beta isozyme,catalytic subunit,delta isoform,MGC3672,PP 1B,Protein phosphatase 1,Protein phosphatase 1 beta,Protein phosphatase 1 catalytic subunit beta isoform,Protein phosphatase 1 delta,Serine threonine protein phosphatase PP1 beta catalytic subunit,Serine/threonine-protein phosphatase PP1-beta catalytic subunit,Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the 'Ser-418' residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 37 kDa

Observed MW: 35 kDa The actual band is not consistent with the expectation.

UniProt: P62140

Pathways: M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism