PPP1CB Antikörper (AA 155-250)

Produktnummer ABIN725465

Produktdetails anti-PPP1CB Antikörper

Target: PPP1CB (Protein Phosphatase 1, Catalytic Subunit, beta Isoform (PPP1CB))

Bindungsspezifität: AA 155-250

Reaktivität: Ratte

Wirt: Maus

Klonalität: Polyklonal

Konjugat: Dieser PPP1CB Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Cow,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PP-1B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu PPP1CB

Target: PPP1CB (Protein Phosphatase 1, Catalytic Subunit, beta Isoform (PPP1CB))

Andere Bezeichnung: PP-1B (PPP1CB Produkte)

Hintergrund:

Synonyms: PP1B, PP-1B, PPP1CD, PP1beta, HEL-S-8p, Serine/threonine-protein phosphatase PP1-beta catalytic subunit, PPP1CB

Background: Protein phosphatase that associates with over 2 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E.

Gen-ID: 5500

UniProt: P62140

Pathways: M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism