PPP1CB Antikörper (Catalytic Subunit)

Produktnummer ABIN7169308

Produktdetails anti-PPP1CB Antikörper

Target: PPP1CB (Protein Phosphatase 1, Catalytic Subunit, beta Isoform (PPP1CB))

Bindungsspezifität: AA 175-221, Catalytic Subunit

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP1CB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Serine/threonine-protein phosphatase PP1-beta catalytic subunit protein (175-221AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PPP1CB

Target: PPP1CB (Protein Phosphatase 1, Catalytic Subunit, beta Isoform (PPP1CB))

Andere Bezeichnung: PPP1CB (PPP1CB Produkte)

Hintergrund:

Background: Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the \\\'Ser-418\\\' residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208).

Aliases: MGC3672 antibody, PP 1B antibody, PP-1B antibody, PP1B antibody, PP1B_HUMAN antibody, PP1beta antibody, PPP1CB antibody, PPP1CD antibody, Protein phosphatase 1 beta antibody, Protein phosphatase 1 catalytic subunit beta isoform antibody, Protein phosphatase 1 delta antibody, Protein phosphatase 1, catalytic subunit, beta isozyme antibody, Protein phosphatase 1, catalytic subunit, delta isoform antibody, Serine threonine protein phosphatase PP1 beta catalytic subunit antibody, Serine/threonine-protein phosphatase PP1-beta catalytic subunit antibody

UniProt: P62140

Pathways: M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism