Rekombinanter MEK2 Antikörper

Produktnummer ABIN7828397

Der Kaninchen Monoklonal anti-MEK2 Antikörper wird verwendet zum Nachweis von MEK2 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und IHC.

Kurzübersicht für Rekombinanter MEK2 Antikörper (ABIN7828397)

Target: MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser MEK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: A302

Produktdetails anti-MEK2 Antikörper

Verwendungszweck: Recombinant MEK2 Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human MEK2 fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000,IHC 1:100-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu MEK2

Target: MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))

Andere Bezeichnung: MEK2

Hintergrund: MEK,MKK,CFC,MAPKK,PRKMK,MAP2K,CFC4,MAPKK2,MEK2,MKK2,PRKMK2,MAP2K2,Cardiofaciocutaneous syndrome,CFC syndrome,Dual specificity mitogen activated protein kinase kinase 2,Dual specificity mitogen-activated protein kinase kinase 2,ERK activator kinase 2,FLJ26075,MAP kinase kinase 2,MAPK / ERK kinase 2,MAPK/ERK kinase 2,MAPKK 2,MEK 2,Microtubule associated protein kinase kinase 2,Mitogen activated protein kinase kinase 2,Mitogen activated protein kinase kinase 2 p45,MKK 2,MP2K2,OTTHUMP00000165826,OTTHUMP00000165827,PRKMK 2,The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, cognitive disability, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 44 kDa

Observed MW: 44 kDa

UniProt: P36507

Pathways: MAPK Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling