Rekombinanter FADD Antikörper (pSer194)

Produktnummer ABIN7828195

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch FADD in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter FADD Antikörper (pSer194) (ABIN7828195)

Target: FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser FADD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: A808

Produktdetails anti-FADD Antikörper

Bindungsspezifität: pSer194

Verwendungszweck: Recombinant Phospho-FADD (S194) Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human FADD (phospho S194) fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu FADD

Target: FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))

Andere Bezeichnung: FADD

Hintergrund: GIG,MORT,FADD,GIG3,MORT1,Fas associated via death domain,FADD protein,Fas (TNFRSF6) associated via death domain,Fas associating death domain containing protein,Fas associating protein,Fas associating protein with death domain,Fas TNFRSF6 associated via death domain,FAS-associated death domain protein,FAS-associating death domain-containing protein,GIG 3,Growth inhibiting gene 3 protein,Growth-inhibiting gene 3 protein,H sapiens mRNA for mediator of receptor induced toxicity,Mediator of receptor induced toxicity,MGC8528,MORT 1,Protein FADD,The protein is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 23 kDa

Observed MW: 23 kDa

UniProt: Q13158

Pathways: Apoptose, TLR Signalweg, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades