Rekombinanter CD40 Antikörper

Produktnummer ABIN7828084

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch CD40 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter CD40 Antikörper (ABIN7828084)

Target: CD40

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CD40 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: A417

Produktdetails anti-CD40 Antikörper

Verwendungszweck: Recombinant CD40 Monoclonal Antibody

Aufreinigung: Protein A purified

Immunogen: Recombinant human CD40 fragment

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:5000,IHC 1:200-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu CD40

Target: CD40

Andere Bezeichnung: CD40

Hintergrund: CDW,B-cell surface antigen CD,Tumor necrosis factor receptor superfamily member,TNFRSF,CD40,Bp50,CDW40,TNFRSF5,p50,Tumor necrosis factor receptor superfamily member 5,B-cell surface antigen CD40,CD40L receptor,TNFRSF5,AI326936,B cell associated molecule CD40,B cell surface antigen CD40,B cell-associated molecule,CD 40,CD40 (protein),CD40 antigen,CD40 antigen (TNF receptor superfamily member 5),CD40 Molecule,CD40 protein,CD40 type II isoform,GP39,HIGM1,IGM,IMD3,isoform CRA_a,member 5,MGC9013,Nerve growth factor receptor related B lymphocyte activation molecule,OTTHUMP00000031699,OTTHUMP00000031700,TBAM,T-BAM,TNF receptor superfamily member 5,TNR5,TRAP,Tumor necrosis factor receptor superfamily,Tumor necrosis factor receptor superfamily member 5 precursor,The CD40 antigen is a 44-48 kDa type I integral membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. This antigen is found on B cell lines, is strongly expressed by interdigitating cells (IDC), basal epithelial cells, and is also present on macrophages, some endothelial cells, and follicular dendritic cells. It is a well-known regulator of T cell immunity including in cancer. CD40-ligand, primarily expressed on activated T cells, interacts with CD40 on APCs resulting in a 'licensed' state. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molekulargewicht:

Calculated MW: 32 kDa

Observed MW: 44-48 kDa The actual band is not consistent with the expectation.

UniProt: P25942

Pathways: NF-kappaB Signalweg, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints