IL-6 Antikörper (AA 101-150)

Produktnummer ABIN739385

Der Kaninchen Polyklonal Anti-IL-6-Antikörper wurde für WB, ELISA, IF (p), IHC (p), IF (cc) und IHC (fro) validiert. Er ist geeignet, IL-6 in Proben von Maus und Ratte zu detektieren. Es sind 12+ Publikationen verfügbar.

Kurzübersicht für IL-6 Antikörper (AA 101-150) (ABIN739385)

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-IL-6 Antikörper

Bindungsspezifität: AA 101-150

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse IL-6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-IL-6 Antikörper (ABIN739385)

Ding, Ren, Yu, Yu, Zhou: "Porphyromonas gingivalis, a periodontitis causing bacterium, induces memory impairment and age-dependent neuroinflammation in mice." in: Immunity & ageing : I & A, Vol. 15, pp. 6, (2018) (PubMed).

Xi, Wang, Chen, Yang, Hu, Zhang, Weng, Xu: "Expressions of IL-6, TNF-α and NF-κB in the skin of Chinese brown frog (Rana dybowskii)." in: European journal of histochemistry : EJH, Vol. 61, Issue 4, pp. 2834, (2018) (PubMed).

Ehrnthaller, Huber-Lang, Kovtun, Rapp, Kemmler, Gebhard, Ignatius: "C5aR inhibition in the early inflammatory phase does not affect bone regeneration in a model of uneventful fracture healing." in: European journal of medical research, Vol. 21, Issue 1, pp. 42, (2017) (PubMed).

Hong, Huang, Liu, Tsai: "Djulis (Chenopodium formosanum Koidz.) Water Extract and Its Bioactive Components Ameliorate Dermal Damage in UVB-Irradiated Skin Models." in: BioMed research international, Vol. 2016, pp. 7368797, (2017) (PubMed).

Chang, Chen, Hsu, Huang, Wu, Hsu: "Protective effects of the roots of Angelica sinensis on strenuous exercise-induced sports anemia in rats." in: Journal of ethnopharmacology, Vol. 193, pp. 169-178, (2016) (PubMed).

Wang, Gu, Liu, Bai, Wang: "Fluoxetine protects against methamphetamine‑induced lung inflammation by suppressing oxidative stress through the SERT/p38 MAPK/Nrf2 pathway in rats." in: Molecular medicine reports, Vol. 15, Issue 2, pp. 673-680, (2016) (PubMed).

Elkabir, El-Zehery, Mourad, Soliman, Helal, Refai, Grawish: "Efficacy of azithromycin and metronidazole combined therapy on rats' gingival overgrowth induced by cyclosporine-A: An experimental animal study." in: Journal of oral biology and craniofacial research, Vol. 6, Issue 3, pp. 219-226, (2016) (PubMed).

Kemmler, Bindl, McCook, Wagner, Gröger, Wagner, Scheuerle, Radermacher, Ignatius: "Exposure to 100% Oxygen Abolishes the Impairment of Fracture Healing after Thoracic Trauma." in: PLoS ONE, Vol. 10, Issue 7, pp. e0131194, (2016) (PubMed).

Li, Dan, Nie, Hu, Gesang, Bianba, Ze, Ciren: "CD14 knockdown reduces lipopolysaccharide-induced cell viability and expression of inflammation-associated genes in gastric cancer cells in vitro and in nude mouse xenografts." in: Molecular medicine reports, Vol. 12, Issue 3, pp. 4332-9, (2015) (PubMed).

Mohamed, El-Zehery, Mourad, Grawish: "Impact of three different mouthwashes on the incidence of gingival overgrowth induced by cyclosporine-A: a randomized controlled experimental animal study." in: Oral surgery, oral medicine, oral pathology and oral radiology, Vol. 120, Issue 3, pp. 346-56, (2015) (PubMed).

Chenna Narendra, Chalise, Magnusson, Uppugunduri: "Local but Not Systemic Administration of Uridine Prevents Development of Antigen-Induced Arthritis." in: PLoS ONE, Vol. 10, Issue 10, pp. e0141863, (2015) (PubMed).

Details zu IL-6

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Andere Bezeichnung: IL-6

Hintergrund:

Synonyms: Il-6, Interleukin-6, B-cell hybridoma growth factor, Interleukin HP-1, Il6

Background: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.

Gen-ID: 16193

UniProt: P08505

Pathways: TLR Signalweg, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagie, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome