NRF2 Antikörper (AA 430-480) (Biotin)

Produktnummer ABIN737273

Produktdetails anti-NRF2 Antikörper (Biotin)

Target: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Bindungsspezifität: AA 430-480

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NRF2 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Huhn, Human, Maus, Schwein, Kaninchen, Ratte

Homologie: Dog,Cow,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Nrf2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:100-1000
IHC-P 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu NRF2

Target: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Andere Bezeichnung: Nrf2 (NFE2L2 Produkte)

Synonyme: Nrf2 antikoerper, nfe2l2 antikoerper, wu:fc15g09 antikoerper, wu:fj67e03 antikoerper, NF-E2R2 antikoerper, NRF2 antikoerper, AI194320 antikoerper, nuclear factor, erythroid 2-like 2a antikoerper, nuclear factor, erythroid 2 like 2 S homeolog antikoerper, nuclear factor, erythroid 2 like 2 antikoerper, nuclear factor, erythroid derived 2, like 2 antikoerper, nuclear factor, erythroid 2-like 2 antikoerper, nfe2l2a antikoerper, nfe2l2.S antikoerper, NFE2L2 antikoerper, Nfe2l2 antikoerper

Hintergrund:

Synonyms: NRF2, Nuclear factor erythroid 2-related factor 2, NF-E2-related factor 2, NFE2-related factor 2, HEBP1, Nuclear factor, erythroid derived 2, like 2, NFE2L2

Background: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.

Gen-ID: 4780

UniProt: Q16236

Pathways: ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling