Rekombinanter Cyclin A Antikörper (C-Term)

Produktnummer ABIN7795811

Dieser Kaninchen Monoklonal Antikörper erkennt spezifisch Cyclin A in WB, IHC, IP und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Rekombinanter Cyclin A Antikörper (C-Term) (ABIN7795811)

Target: Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Cyclin A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Klon: BLR369N

Produktdetails anti-Cyclin A Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Rabbit anti-CCNA2/Cyclin A2 Recombinant Monoclonal Antibody [BLR369N]

Aufreinigung: Purified

Immunogen: between 382 and 432 (C-term)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,WB,11,000,IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,IP,12 μL/mg lysate

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 500 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2 - 8 °C

Haltbarkeit: 12 months

Details zu Cyclin A

Target: Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

Andere Bezeichnung: CCNA2/Cyclin A2

Hintergrund: The protein encoded by the gene CCNA2, Cyclin A2, belongs to the highly conserved cyclin family. Members of the cyclin family are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, Cyclin A2 is expressed in all tissues tested. Cyclin A2 binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions [taken from NCBI Entrez Gene ID: 890].

Gen-ID: 890

UniProt: P20248

Pathways: PI3K-Akt Signalweg, Zellzyklus, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA