Rekombinanter c-MET Antikörper (C-Term)

Produktnummer ABIN7795683

Der Kaninchen Monoklonal Anti-c-MET Antikörper wurde für WB, IHC, FACS, ICC und IP validiert. Er ist geeignet, c-MET in Proben von Human zu detektieren.

Kurzübersicht für Rekombinanter c-MET Antikörper (C-Term) (ABIN7795683)

Target: c-MET (MET) (Met Proto-Oncogene (MET))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser c-MET Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Klon: BLR283L

Produktdetails anti-c-MET Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Rabbit anti-Met Recombinant Monoclonal Antibody [BLR283L]

Aufreinigung: Purified

Immunogen: Between 1340 and C-terminus

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow-Cyt,Fixed in 4 % formaldehyde and permeabilized with 90 % methanol. 0.5 μL per 1 x 10^6 cells.,ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,IP,6 μL/mg lysate ,WB,11000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2 - 8 °C

Haltbarkeit: 12 months

Details zu c-MET

Target: c-MET (MET) (Met Proto-Oncogene (MET))

Andere Bezeichnung: Met

Hintergrund: The proto-oncogene MET is a member of the receptor tyrosine kinase family of proteins. The preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. [taken from NCBI Entrez Gene (Gene ID: 4233)].

Gen-ID: 4233

UniProt: P08581

Pathways: RTK Signalweg, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor