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c-MET Antikörper (C-Term)

Name: c-MET Antikörper (C-Term)
Brand: antibodies-online
SKU: ABIN2854819
Price: 630.63 EUR
Availability: InStock

MET Reaktivität: Human WB, IF, ICC, IP Wirt: Kaninchen Polyclonal unconjugated

WB Image Sample(30 ug whole cell lysate) A:HeLa S3, 5% SDS PAGE antibody diluted at 1:1000

ICC/IF Image c-Met antibody [c3], c-term detects c-Met protein at cytoplasm by immunofluorescent analysis.

IHC-P Image Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using c-Met, antibody at 1:100 dilution.

IHC

IP Image Immunoprecipitation of c-Met protein from HeLa whole cell extracts using 5 μg of c-Met antibody [C3], C-term, Western blot analysis was performed using c-Met antibody [C3], C-term, EasyBlot anti-Rabbit IgG was used as a secondary reagent.

MUC20 knockdown inhibits HGF/MET signalling in PDAC cells.

5 Abbildungen

Produktnummer ABIN2854819

Datenblatt (PDF)

Target Alle c-MET (MET) Antikörper anzeigen

c-MET (MET) (Met Proto-Oncogene (MET))
Bindungsspezifität
49

35

28

21

16

11

11

8

7

7

7

6

5

5

4

4

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
Reaktivität
250

144

98

8

6

4

4

4

2

2

2

1

1

1

1
Human
Wirt
221

39

3

2
Kaninchen
Passende Sekundärantikörper
Klonalität
209

56
Polyklonal
Konjugat
131

20

13

12

9

9

9

9

9

9

8

7

3

3

3

3

3

1

1

1

1

1
Dieser c-MET Antikörper ist unkonjugiert
Applikation
181

105

51

43

30

27

26

24

14

8

7

7

4

4

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Kreuzreaktivität

Schimpanse

Kreuzreaktivität (Details)

Chimpanzee (100 %)

Produktmerkmale

Rabbit Polyclonal antibody to MET (met proto-oncogene (hepatocyte growth factor receptor))
c-Met antibody [C3], C-term

Aufreinigung

Purified by antigen-affinity chromatography.

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human c-Met. The exact sequence is proprietary.

Isotyp

IgG

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Applikationshinweise

Suggested dilution Reference ICC/IF 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:500-1:3000*

Kommentare

Positive Control: HeLaS3

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel

Thimerosal (Merthiolate)

Vorsichtsmaßnahmen

This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Target

c-MET (MET) (Met Proto-Oncogene (MET))

Andere Bezeichnung

C-Met (MET Produkte)

Synonyme

AUTS9 antikoerper, HGFR antikoerper, RCCP2 antikoerper, c-Met antikoerper, AI838057 antikoerper, HGF antikoerper, Par4 antikoerper, Hgfr antikoerper, c-met antikoerper, MET antikoerper, C-MET antikoerper, met antikoerper, met-A antikoerper, MET proto-oncogene, receptor tyrosine kinase antikoerper, met proto-oncogene antikoerper, MET proto-oncogene, receptor tyrosine kinase L homeolog antikoerper, MET antikoerper, Met antikoerper, met.L antikoerper

Hintergrund

The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Membrane, Single-pass type I membrane protein

Molekulargewicht

156 kDa

Gen-ID

4233

Pathways

RTK Signalweg, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor