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c-MET Antikörper (AA 743-932)

MET Reaktivität: Human, Affe WB, ELISA, IHC, FACS, ICC Wirt: Maus Monoclonal 5E9C4 unconjugated
Produktnummer ABIN5542707
  • Target Alle c-MET (MET) Antikörper anzeigen
    c-MET (MET) (Met Proto-Oncogene (MET))
    Bindungsspezifität
    • 49
    • 35
    • 28
    • 21
    • 16
    • 12
    • 11
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 743-932
    Reaktivität
    • 250
    • 144
    • 98
    • 8
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Affe
    Wirt
    • 222
    • 38
    • 3
    • 2
    Maus
    Klonalität
    • 210
    • 55
    Monoklonal
    Konjugat
    • 131
    • 20
    • 13
    • 12
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 8
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser c-MET Antikörper ist unkonjugiert
    Applikation
    • 181
    • 104
    • 50
    • 42
    • 31
    • 27
    • 26
    • 24
    • 14
    • 8
    • 8
    • 7
    • 4
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Immunogen
    Purified recombinant fragment of human MET (AA 743-932) expressed in E. Coli.
    Klon
    5E9C4
    Isotyp
    IgG1
    Top Product
    Discover our top product MET Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.05 % sodium azide
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Target
    c-MET (MET) (Met Proto-Oncogene (MET))
    Andere Bezeichnung
    MET (MET Produkte)
    Synonyme
    AUTS9 antikoerper, HGFR antikoerper, RCCP2 antikoerper, c-Met antikoerper, AI838057 antikoerper, HGF antikoerper, Par4 antikoerper, Hgfr antikoerper, c-met antikoerper, MET antikoerper, C-MET antikoerper, met antikoerper, met-A antikoerper, MET proto-oncogene, receptor tyrosine kinase antikoerper, met proto-oncogene antikoerper, MET proto-oncogene, receptor tyrosine kinase L homeolog antikoerper, MET antikoerper, Met antikoerper, met.L antikoerper
    Hintergrund
    This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers.,
    Molekulargewicht
    71.3kDa
    HGNC
    6925
    Pathways
    RTK Signalweg, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
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