Rekombinanter CTLA4 Antikörper

Produktnummer ABIN7795354

Der Maus Monoklonal anti-CTLA4 Antikörper (Klon 9D9) (ABIN7795354) detektiert spezifisch CTLA4 in WB, FACS, IHC, ELISA, ICC und in vivo. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für Rekombinanter CTLA4 Antikörper (ABIN7795354)

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Antikörpertyp: Recombinant Antibody

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CTLA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), In vivo Studies (in vivo)

Güteklasse: In vivo Grade

Klon: 9D9

Produktdetails anti-CTLA4 Antikörper

Expressionssystem: Mammalian cells

Verwendungszweck: In vivo Grade Recombinant Anti-mouse CTLA-4 Monoclonal Antibody, Mouse IgG2c-L234A L235A P329G (LALAPG) Kappa (Clone: 9D9)

Produktmerkmale: The 9D9 antibody blocks the mouse cytotoxic T lymphocyte antigen-4 (CTLA-4). Blocking CTLA-4 removes an inhibitory signal from reducing the activity of T lymphocytes. Cytotoxic T-lymphocyte antigen-4 (CTLA-4) is an inhibitory molecule that competes with the stimulatory CD28 for binding to B7 on antigen presenting cells. CTLA-4 and CD28 are both presented on the surface of T-cells.

Aufreinigung: Protein A or G affinity column

Reinheit: >95 % by reducing SDS-PAGE

Endotoxin-Niveau: < 1 EU per 1 mg of the protein by the LAL method

Isotyp: IgG2c, L234A, L235A, P329G

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: > 3 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Details zu CTLA4

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Andere Bezeichnung: CTLA-4

Pathways: Cancer Immune Checkpoints