ULK1 Antikörper (pSer556)
Kurzübersicht für ULK1 Antikörper (pSer556) (ABIN7674408)
Target
Alle ULK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- pSer556
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Verwendungszweck
- Phospho-ULK1 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
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Immunogen sequence: Peptide
Immunogen: peptide
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Haltbarkeit
- 12 months
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- ULK1 (Unc-51 Like Kinase 1 (ULK1))
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Andere Bezeichnung
- ULK1ULK1
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Hintergrund
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Synonyms: Serine/threonine-protein kinase ULK1|Autophagy-related protein 1 homolog (ATG1, hATG1)|Unc-51-like kinase 1|ULK1|KIAA0722
Background: ULK1, also named as KIAA0722, belongs to the protein kinase superfamily, Ser/Thr protein kinase family and APG1/unc-51/ULK1 subfamily. It is involved in autophagy. ULK1 is required for autophagosome formation. It forms a stable complex with Atg13 and focal adhesion kinase(FAK) family interacting protein of 200 kDa(FIP 200)(PMID:21460634). ULK1 phosphorylates ATG13/KIAA0652. It is involved in axon growth. ULK1 plays an essential role in neurite extension of cerebellar granule cells. ULK1 represents a potential novel prognostic biomarker for HCC patients and may play an important role during the progression of HCC(PMID:23573318).
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Molekulargewicht
- 140-150 kDa
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Gen-ID
- 8408
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UniProt
- O75385
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Pathways
- Regulation of Cell Size, Autophagie
Target
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