Caspase 9 Antikörper
Kurzübersicht für Caspase 9 Antikörper (ABIN7670508)
Target
Alle Caspase 9 (CASP9) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Caspase-9 Monoclonal Antibody
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Aufreinigung
- Protein A/G Purification
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Immunogen
- Recombinant Human Caspase-9 protein expressed by E.coli
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Isotyp
- IgG2a
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Applikationshinweise
- WB 1:250-1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.05 % proclin 300, 1 % protective protein and 50 % glycerol, pH 7.4
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Haltbarkeit
- 12 months
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- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
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Andere Bezeichnung
- Caspase-9
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Hintergrund
- Apoptosis related cysteine peptidase,Apoptotic protease-activating factor 3,Caspase 9 apoptosis related cysteine peptidase,Caspase 9 Dominant Negative,Caspase 9c,Caspase-9 subunit p10,ICE LAP6,ICE like apoptotic protease 6,ICE-like apoptotic protease 6,protein phosphatase 1,regulatory subunit 56,RNCASP9,MCH,Apoptotic protease Mch,PPP1R,ICE-LAP,CASP9,APAF-3,APAF3,ICE-LAP6,MCH6,PPP1R56,caspase-9,Caspase 9,CASP-9,Apoptotic protease Mch-6,Apoptotic protease-activating factor 3 (APAF-3),ICE-like apoptotic protease 6 (ICE-LAP6),Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
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Molekulargewicht
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Calculated MW: 46 kDa
ObservedMW: 35 kDa,47 kDa
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UniProt
- P55211
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Pathways
- MAPK Signalweg, RTK Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Endopeptidase Activity
Target
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