CD40 Antikörper

Produktnummer ABIN7670020

Der Maus Monoklonal Anti-CD40-Antikörper wurde für FACS validiert. Er ist geeignet, CD40 in Proben von Human zu detektieren.

Kurzübersicht für CD40 Antikörper (ABIN7670020)

Target: CD40

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD40 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: 3A8

Produktdetails anti-CD40 Antikörper

Verwendungszweck: Purified Anti-Human CD40 Antibody[3A8]

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: avoid freeze / thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu CD40

Target: CD40

Andere Bezeichnung: CD40

Hintergrund: CDW,B-cell surface antigen CD,Tumor necrosis factor receptor superfamily member,TNFRSF,CD40,Bp50,CDW40,TNFRSF5,p50,Tumor necrosis factor receptor superfamily member 5,B-cell surface antigen CD40,CD40L receptor, TNFRSF5,AI326936,B cell associated molecule CD40,B cell surface antigen CD40,B cell-associated molecule,CD 40,CD40 (protein),CD40 antigen,CD40 antigen (TNF receptor superfamily member 5),CD40 Molecule,CD40 protein,CD40 type II isoform,GP39,HIGM1,IGM,IMD3,isoform CRA_a,member 5,MGC9013,Nerve growth factor receptor related B lymphocyte activation molecule,OTTHUMP00000031699,OTTHUMP00000031700,TBAM,T-BAM,TNF receptor superfamily member 5,TNR5,TRAP,Tumor necrosis factor receptor superfamily,Tumor necrosis factor receptor superfamily member 5 precursor,CD40 is a type I transmembrane glycoprotein belonging to the TNF receptor superfamily. The mature hCD40 consists of a 172 amino acid (aa) extracellular domain, a 22 aa transmembrane region and a 62 aa cytoplasmic domain . Human and mouse CD40 share 62 % aa identity. CD40 is expressed in B cells, follicular dendritic cells, dendritic cells, activated monocytes, macrophages, endothelial cells, vascular smooth muscle cells, and several tumor cell lines.

UniProt: P25942

Pathways: NF-kappaB Signalweg, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints