JNK Antikörper (pThr183, pTyr185) (Biotin)
Kurzübersicht für JNK Antikörper (pThr183, pTyr185) (Biotin) (ABIN732370)
Target
Alle JNK (MAPK8) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
 - pThr183, pTyr185
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Kreuzreaktivität
 - Hund, Human, Maus, Kaninchen, Ratte
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Homologie
 - Cow,Pig
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Aufreinigung
 - Purified by Protein A.
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Immunogen
 - KLH conjugated synthetic phosphopeptide derived from human JNK1 around the phosphorylation site of Thr183/Tyr185
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Isotyp
 - IgG
 
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Applikationshinweise
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                        WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 
                                            
Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Format
 - Liquid
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Konzentration
 - 1 μg/μL
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Buffer
 - Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
 - ProClin
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Vorsichtsmaßnahmen
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
 - -20 °C
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Informationen zur Lagerung
 - Store at -20°C for 12 months.
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Haltbarkeit
 - 12 months
 
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- JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))
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Andere Bezeichnung
 - JNK1+2+3
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Hintergrund
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Synonyms: JNK, JNK1, PRKM8, SAPK1, JNK-46, JNK1A2, SAPK1c, JNK21B1/2, Mitogen-activated protein kinase 8, MAP kinase 8, MAPK 8, Stress-activated protein kinase 1c, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1, MAPK8
Background: JNK1 isoforms display different binding patterns: beta-1 preferentially binds to c-Jun, whereas alpha-1, alpha-2, and beta-2 have a similar low level of binding to both c-Jun or ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms.
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Gen-ID
 - 5599
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UniProt
 - P45983
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Pathways
 - MAPK Signalweg, WNT Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteine
 
Target
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