PYCARD Antikörper

Produktnummer ABIN7606534

Der Kaninchen Monoklonal Anti-PYCARD-Antikörper wurde für WB, IF, FACS und ICC validiert. Er ist geeignet, PYCARD in Proben von Human zu detektieren.

Kurzübersicht für PYCARD Antikörper (ABIN7606534)

Target: PYCARD (PYD and CARD Domain Containing (PYCARD))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PYCARD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Klon: FFB-16

Produktdetails anti-PYCARD Antikörper

Verwendungszweck: Anti-TMS1 PYCARD Rabbit Monoclonal Antibody

Produktmerkmale: Anti-TMS1 PYCARD Rabbit Monoclonal Antibody (ABIN7606534). Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.

Aufreinigung: Affinity-chromatography

Immunogen: A synthesized peptide derived from human TMS1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000
ICC/IF 1:50-1:200
FC 150

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Konzentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Details zu PYCARD

Target: PYCARD (PYD and CARD Domain Containing (PYCARD))

Andere Bezeichnung: PYCARD

Hintergrund:

Synonyms: Apoptosis-associated speck-like protein containing a CARD,hASC,Caspase recruitment domain-containing protein 5,PYD and CARD domain-containing protein,Target of methylation-induced silencing 1,PYCARD,ASC, CARD5, TMS1,

Tissue Specificity: Widely expressed at low levels. Detected in peripheral blood leukocytes, lung, small intestine, spleen, thymus, colon and at lower levels in placenta, liver and kidney. Very low expression in skeletal muscle, heart and brain. Detected in the leukemia cell lines HL-60 and U-937, but not in Jurkat T- cell lymphoma and Daudi Burkitt's lymphoma. Detected in the melanoma cell line WM35, but not in WM793. Not detected in HeLa cervical carcinoma cells and MOLT-4 lymphocytic leukemia cells.

Molekulargewicht: 53 kDa

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation, Inflammasome