IRAK4 Antikörper
Kurzübersicht für IRAK4 Antikörper (ABIN7605308)
Target
Alle IRAK4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-IRAK4 Monoclonal Antibody
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Produktmerkmale
- Anti-IRAK4 Monoclonal Antibody (ABIN7605308). Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.
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Aufreinigung
- Affinity-chromatography
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Immunogen
- A synthesized peptide derived from human IRAK4 Required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Phosphorylates IRAK1.
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Isotyp
- IgG
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Applikationshinweise
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WB 1:500-1:2000
IHC 1:50-1:200
ICC/IF 1:50-1:200
FC 1:50 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Rekonstitution
- Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
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Konzentration
- Lot specific
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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- IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
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Andere Bezeichnung
- IRAK4
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Hintergrund
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Synonyms: Occludin,OCLN,
Tissue Specificity: Localized at tight junctions of both epithelial and endothelial cells. Highly expressed in kidney. Not detected in testis.
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Molekulargewicht
- 80 kDa
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Pathways
- NF-kappaB Signalweg, TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades
Target
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