FADD Antikörper
Kurzübersicht für FADD Antikörper (ABIN7604814)
Target
Alle FADD Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-FADD Monoclonal Antibody
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Produktmerkmale
- Anti-FADD Monoclonal Antibody-1. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Mouse.
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Aufreinigung
- Affinity-chromatography
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Immunogen
- A synthesized peptide derived from human FADD Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-2000IHC 1:50-200FC 1:20
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
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Andere Bezeichnung
- Fadd
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Hintergrund
- Fas associated via death domain
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Molekulargewicht
- 100-110 kDa
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Gen-ID
- 14082
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UniProt
- Q61160
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Pathways
- Apoptose, TLR Signalweg, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
Target
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