NRF2 Antikörper (AA 67-601)
Kurzübersicht für NRF2 Antikörper (AA 67-601) (ABIN7602273)
Target
Alle NRF2 (NFE2L2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 67-601
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Verwendungszweck
- Anti-NRF2/NFE2L2 Antibody
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Produktmerkmale
- Anti-NRF2/NFE2L2 Antibody (ABIN7602273). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human NRF2/NFE2L2 recombinant protein (Position: E67-D601).
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Isotyp
- IgG
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Applikationshinweise
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg /1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Konzentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
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Andere Bezeichnung
- NFE2L2
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Hintergrund
- Nuclear factor erythroid 2-related factor 2 (NRF2), also known as nuclear factor erythroid-derived 2-like 2, is a transcription factor that in humans is encoded by the NFE2L2 gene. This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters, many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene.
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Molekulargewicht
- 100-110 kDa
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Gen-ID
- 4780
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UniProt
- Q16236
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Pathways
- ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling
Target
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