Growth Hormone Receptor Antikörper (AA 19-638)

Produktnummer ABIN7600424

Dieser Anti-Growth Hormone Receptor Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von Growth Hormone Receptor in WB, ELISA, IHC, ICC, FACS und IF. Geeignet für Human.

Kurzübersicht für Growth Hormone Receptor Antikörper (AA 19-638) (ABIN7600424)

Target: Growth Hormone Receptor (GHR)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Growth Hormone Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF)

Produktdetails anti-Growth Hormone Receptor Antikörper

Bindungsspezifität: AA 19-638

Verwendungszweck: Anti-Growth hormone receptor/GHR Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Growth hormone receptor/GHR Antibody (ABIN7600424). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Growth hormone receptor/GHR recombinant protein (Position: F19-P638).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu Growth Hormone Receptor

Target: Growth Hormone Receptor (GHR)

Andere Bezeichnung: GHR

Hintergrund:

Synonyms: Growth hormone receptor, GH receptor, Somatotropin receptor, Growth hormone-binding protein, Growth hormone-binding protein,

Tissue Specificity: Expressed in lung and placenta.

Background: Growth hormone receptor is a protein that in humans is encoded by the GHR gene. It is mapped to 5p13.1-p12. This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.

Molekulargewicht: 80 kDa

Gen-ID: 2690

UniProt: P10912

Pathways: NF-kappaB Signalweg, JAK-STAT Signalweg, Response to Growth Hormone Stimulus