IGF1 Antikörper (AA 49-100)

Produktnummer ABIN723605

Der Kaninchen Polyklonal Anti-IGF1-Antikörper wurde für WB, IP, ELISA, IF (p), IF (cc), IHC (p) und IHC (fro) validiert. Er ist geeignet, IGF1 in Proben von Human, Maus, Ratte und Hund zu detektieren. Es sind 5+ Publikationen verfügbar.

Kurzübersicht für IGF1 Antikörper (AA 49-100) (ABIN723605)

Target: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IGF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-IGF1 Antikörper

Bindungsspezifität: AA 49-100

Kreuzreaktivität: Hund, Human, Maus, Ratte

Homologie: Cow,Sheep,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IGF-1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
IP(1-2 μg)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-IGF1 Antikörper (ABIN723605)

Liao, Xiao, Zhu, Zhou: "The effect of celastrol on learning and memory in diabetic rats after sevoflurane inhalation." in: Archives of medical science : AMS, Vol. 14, Issue 2, pp. 370-380, (2018) (PubMed).

Uysal, Agilkaya, Sisman, Camsari, Gencoglu, Dayi, Aksu, Baykara, Cingoz, Kiray: "Exercise increases leptin levels correlated with IGF-1 in hippocampus and prefrontal cortex of adolescent male and female rats." in: Journal of chemical neuroanatomy, Vol. 81, pp. 27-33, (2017) (PubMed).

Gabr, Rateb, El Sissy, Ahmed Seddiek, Ali Abdelhameed Gouda: "The effect of bone marrow-derived mesenchymal stem cells on chemotherapy induced ovarian failure in albino rats." in: Microscopy research and technique, Vol. 79, Issue 10, pp. 938-947, (2016) (PubMed).

Kiray, Sisman, Camsari, Evren, Dayi, Baykara, Aksu, Ates, Uysal: "Effects of carbon dioxide exposure on early brain development in rats." in: Biotechnic & histochemistry : official publication of the Biological Stain Commission, Vol. 89, Issue 5, pp. 371-83, (2014) (PubMed).

Baykara, Aksu, Buyuk, Kiray, Sisman, Baykara, Dayi, Tas, Ozdemir, Arda, Uysal et al.: "Progesterone treatment decreases traumatic brain injury induced anxiety and is correlated with increased serum IGF-1 levels; prefrontal cortex, amygdala, hippocampus neuron density; and reduced serum ..." in: Biotechnic & histochemistry : official publication of the Biological Stain Commission, Vol. 88, Issue 5, pp. 250-7, (2013) (PubMed).

Details zu IGF1

Target: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Andere Bezeichnung: IGF 1

Hintergrund:

Synonyms: IGFI, IGF-I, IGF1A, Insulin-like growth factor I, Mechano growth factor, MGF, Somatomedin-C, IGF1, IBP1

Background: The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation.

Gen-ID: 3479

UniProt: P05019

Pathways: RTK Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagie, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation