MAPK14 Antikörper (pThr180, pTyr182)

Produktnummer ABIN7540583

Hersteller Produkt- Nr.: 600-401-c90

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MAPK14 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Ratte.

Kurzübersicht für MAPK14 Antikörper (pThr180, pTyr182) (ABIN7540583)

Target: MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPK14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-MAPK14 Antikörper

Bindungsspezifität: pThr180, pTyr182

Hersteller Produkt- Nr.: 600-401-c90

Hersteller: Rockland

Verwendungszweck: p38 MAPK phospho T180/phospho Y182 Antibody

Kreuzreaktivität (Details): antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities.

Aufreinigung: Anti-p38 MAPK pT180/pY182 Antibody is directed against p38 MAPK phosphorylated at T180 and Y182.

Immunogen: Anti-p38 MAPK pT180/pY182 Antibody was produced by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Thr180/Tyr182.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry_Dilution: 1:250

Western_Blot_Dilution: 1:1000

Other: User Optimized

Kommentare:

Anti-p38 MAPK pT180/pY182 Antibody is tested for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 39kDa in size corresponding to p38 MAPK protein phosphorylated at Thr180/Tyr182 in the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu MAPK14

Target: MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

Andere Bezeichnung: Mapk14

Hintergrund: Mitogen-activated protein kinase 14, MAP kinase 14, MAPK 14, CRK1, Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha,p38 MAPK pT180/pY182 Antibody detects phosphorylated p38 MAPK protein. The three Mitogen-Activated Protein Kinases (MAPKs) are evolutionarily conserved protein kinases that control a vast array of cellular processes. p38 MAPK is one of these kinases and it is activated by both inflammatory cytokines and by stress. The p38 MAPK is thought to be particularly important in diseases like asthma and autoimmunity but it also plays important roles in the stress response of the nervous system. Like the other MAPKs, p38 is activated by a dual specificity kinase that phosphorylates Thr180 and Tyr182. Anti-p38 MAPK pT180/pY182 Antibody is ideal for investigators involved in Signal Transduction and Apoptosis research.

Gen-ID: 70496

NCBI Accession: NM_031020

UniProt: P70618

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagie, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteine