PKC gamma Antikörper (AA 87-338)

Produktnummer ABIN7539851

Dieses Anti-PKC gamma-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von PKC gamma in ELISA. Geeignet für Human.

Kurzübersicht für PKC gamma Antikörper (AA 87-338) (ABIN7539851)

Target: PKC gamma (PRKCG) (Protein Kinase C, gamma (PRKCG))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PKC gamma Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 1G5B3

Produktdetails anti-PKC gamma Antikörper

Bindungsspezifität: AA 87-338

Verwendungszweck: PRKCG Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human PRKCG (AA: 87-338) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu PKC gamma

Target: PKC gamma (PRKCG) (Protein Kinase C, gamma (PRKCG))

Andere Bezeichnung: PRKCG

Hintergrund: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14).

Molekulargewicht: 78.4 kDa

Gen-ID: 5582

UniProt: P05129

Pathways: WNT Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGF Signaling