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PKC gamma Antikörper (pThr514)

PRKCG Reaktivität: Human, Maus WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN703285
  • Target Alle PKC gamma (PRKCG) Antikörper anzeigen
    PKC gamma (PRKCG) (Protein Kinase C, gamma (PRKCG))
    Bindungsspezifität
    • 19
    • 15
    • 15
    • 14
    • 11
    • 9
    • 8
    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr514
    Reaktivität
    • 106
    • 95
    • 68
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus
    Wirt
    • 142
    • 5
    • 1
    Kaninchen
    Klonalität
    • 127
    • 21
    Polyklonal
    Konjugat
    • 52
    • 15
    • 13
    • 9
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PKC gamma Antikörper ist unkonjugiert
    Applikation
    • 128
    • 58
    • 39
    • 38
    • 32
    • 17
    • 11
    • 8
    • 7
    • 7
    • 5
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human, Maus
    Homologie
    Rat,Cow,Pig,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human PKC gamma around the phosphorylation site of Thr514
    Isotyp
    IgG
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    Discover our top product PRKCG Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    PKC gamma (PRKCG) (Protein Kinase C, gamma (PRKCG))
    Andere Bezeichnung
    PKC gamma (PRKCG Produkte)
    Synonyme
    PRKCG antikoerper, PKC-gamma antikoerper, PKCC antikoerper, PKCG antikoerper, SCA14 antikoerper, PKCgamma antikoerper, Pkcc antikoerper, Prkcc antikoerper, PKC antikoerper, PKCI antikoerper, Prkc antikoerper, RATPKCI antikoerper, protein kinase C gamma antikoerper, protein kinase C, gamma antikoerper, protein kinase C gamma type antikoerper, PRKCG antikoerper, Prkcg antikoerper, LOC484316 antikoerper
    Hintergrund

    Synonyms: PKCC, PKCG, SCA14, PKC-gamma, Protein kinase C gamma type, PRKCG

    Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). [provided by RefSeq, Jul 2008]

    Gen-ID
    5582
    UniProt
    P05129
    Pathways
    WNT Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGF Signaling
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