MDM2 Antikörper
Kurzübersicht für MDM2 Antikörper (ABIN7539647)
Target
Alle MDM2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- MDM2 Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Synthesized peptide of human MDM2 (AA: ASEQETLVRPKPLLc).
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Isotyp
- IgG2a
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anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 130-230) antibody
MDM2 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (Center) antibodyMDM2 Reaktivität: Human, Maus WB, IF, IHC (p), IP, ICC, ChIP Wirt: Kaninchen Polyclonal unconjugated
anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 101-200) antibodyMDM2 Reaktivität: Human WB, ELISA, IHC (p), PLA, RNAi Wirt: Maus Monoclonal 1A7 unconjugated
anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 141-176) antibodyMDM2 Reaktivität: Human WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB7981 unconjugated
anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 26-169) antibodyMDM2 Reaktivität: Human IHC, ELISA, FACS Wirt: Maus Monoclonal 3C1E3 unconjugated
anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 26-169) antibodyMDM2 Reaktivität: Human ELISA, FACS Wirt: Maus Monoclonal 4A8D12 unconjugated
anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 200-430) antibodyMDM2 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 119-438) antibodyMDM2 Reaktivität: Human WB, IHC, IHC (p) Wirt: Maus Monoclonal 1E6 unconjugated
anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (pSer186) antibodyMDM2 Reaktivität: Human WB, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 393-424) antibodyMDM2 Reaktivität: Human, Maus WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
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Andere Bezeichnung
- MDM2
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Hintergrund
- This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.
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Molekulargewicht
- 55.2 kDa
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Gen-ID
- 4193
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UniProt
- Q00987
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Pathways
- p53 Signalweg, PI3K-Akt Signalweg, Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Autophagie, Ubiquitin Proteasome Pathway
Target
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